It is forseeable that as users get more and more output into their DB that they will approach the 2GB limit of Access. Some possible solutions to this problem are:
1. Under Advanced | VDDT Settings | Output select to print output for only some, not all time steps.
2. Use MS Access to Compact and Repair your database.
3. Create multiple databases for completing your simulations. Note that multiple databases can be opened at the same time in Path and scenario properties can be copied between them.