Hi Randy,
The upcoming release of ST-Sim (2.3.1). Will support a number of commandline utilities for running the model including running iterations and spatial regions for the same scenario in parallel. These commandline utilities can be run on Linux with Mono ( http://www.mono-project.com/Main_Page) installed. Once the software is released we will create some documentation around running the commandline utilities. However, it will still not be possible to run the full UI version of ST-Sim in Linux as at the moment Mono does not provide full support for windows forms.
Regards,
Leonardo